Yuki Hasegawa Selected Research

2-hexadecenoyl-coenzyme A

12/2008

Development of a new enzymatic diagnosis method for very-long-chain Acyl-CoA dehydrogenase deficiency by detecting 2-hexadecenoyl-CoA production and its application in tandem mass spectrometry-based selective screening and newborn screening in Japan.

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Yuki Hasegawa Research Topics

Disease

6	Multiple Acyl Coenzyme A Dehydrogenase Deficiency 12/2022 - 10/2002
6	VLCAD deficiency 01/2022 - 09/2003
5	Methylmalonic acidemia 04/2010 - 12/2006
4	Brain Diseases (Brain Disorder) 06/2021 - 09/2008
4	Trifunctional Protein Deficiency With Myopathy And Neuropathy 01/2020 - 06/2010
4	Inflammation (Inflammations) 01/2017 - 05/2010
3	Secondary Hyperparathyroidism 01/2023 - 01/2022
3	Stroke (Strokes) 01/2023 - 10/2016
3	Infections 01/2023 - 01/2017
3	Metabolic Diseases (Metabolic Disease) 12/2022 - 03/2011
3	Ventricular Tachycardia 01/2022 - 10/2021
3	Acidosis 06/2021 - 06/2015
3	Propionic Acidemia 06/2021 - 04/2010
3	Hyperammonemia 06/2021 - 09/2008
3	Hypoglycemia (Reactive Hypoglycemia) 07/2019 - 09/2008
3	Fatty Liver 07/2019 - 05/2010
3	Medium chain acyl CoA dehydrogenase deficiency 09/2018 - 09/2005
3	Phenylketonurias (Phenylketonuria) 09/2018 - 11/2010
3	Liver Diseases (Liver Disease) 01/2017 - 06/2011
3	Inborn Errors Metabolism (Inborn Errors of Metabolism) 06/2015 - 10/2002
3	Seizures (Absence Seizure) 06/2010 - 05/2002
2	Chronic Kidney Failure (Chronic Renal Failure) 05/2024 - 01/2022
2	Hyperparathyroidism 01/2024 - 10/2023
2	Thrombosis (Thrombus) 12/2023 - 10/2016
2	Atrial Fibrillation 11/2023 - 05/2023
2	Heart Failure 01/2022 - 12/2021
2	Left Ventricular Dysfunction 01/2022 - 12/2021
2	Muscle Weakness 12/2021 - 09/2019
2	Shock 10/2021 - 09/2019
2	Heart Diseases (Heart Disease) 01/2021 - 01/2019
2	Ornithine Carbamoyltransferase Deficiency Disease 11/2020 - 01/2013
2	Venous Thrombosis (Deep-Vein Thrombosis) 05/2020 - 05/2017
2	Fever (Fevers) 01/2017 - 11/2003
2	Rhabdomyolysis 12/2011 - 09/2003
2	Fibrosis (Cirrhosis) 06/2011 - 05/2010
2	Non-alcoholic Fatty Liver Disease 06/2011 - 05/2010
2	Glutaric Acidemia I 03/2011 - 09/2009
2	Hyperthermia 06/2010 - 05/2010
2	Biotinidase Deficiency (Multiple Carboxylase Deficiency, Late Onset) 02/2007 - 04/2003
1	3-Methylglutaconic Aciduria 03/2024
1	Thrombophilia 12/2023
1	Hypercalcemia (Milk Alkali Syndrome) 10/2023
1	Hammer Toe Syndrome (Hammer Toe) 01/2023
1	Cerebral Hemorrhage 01/2023
1	Infarction (Infarctions) 01/2023
1	Lacerations 09/2022
1	Wounds and Injuries (Trauma) 01/2022
1	Muscular Diseases (Myopathy) 01/2022
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2022
1	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2022

Drug/Important Bio-Agent (IBA)

11	Fatty Acids (Saturated Fatty Acids)IBA 09/2019 - 10/2002
8	AcidsIBA 06/2021 - 04/2003
6	acylcarnitineIBA 01/2017 - 08/2007
5	Long-Chain Acyl-CoA Dehydrogenase (Long-Chain-Acyl-Coenzyme A Dehydrogenase)IBA 01/2022 - 09/2003
4	electron-transferring-flavoprotein dehydrogenase (ETF dehydrogenase)IBA 12/2022 - 05/2008
4	Electron-Transferring Flavoproteins (Electron Transfer Flavoprotein)IBA 12/2022 - 05/2008
4	Creatine Kinase (Creatine Phosphokinase)IBA 01/2022 - 06/2015
4	Amino Acids FDA Link 09/2018 - 05/2008
3	Parathyroid Hormone (Parathormone)IBA 01/2024 - 01/2022
3	Carnitine palmitoyl transferase 2 deficiencyIBA 11/2017 - 10/2002
3	Indicators and Reagents (Reagents)IBA 06/2013 - 02/2008
3	Carnitine (L-Carnitine)FDA LinkGeneric 06/2010 - 11/2003
3	Acyl-CoA Dehydrogenase (Medium-Chain Acyl-Coenzyme A Dehydrogenase)IBA 06/2010 - 11/2003
2	Botulinum Toxins (Botulinum Toxin)IBA 01/2023 - 12/2022
2	Riboflavin (Vitamin B2)FDA LinkGeneric 12/2022 - 08/2019
2	Lactic Acid (Lactate)FDA LinkGeneric 08/2019 - 12/2016
2	Ketone BodiesIBA 07/2019 - 06/2015
2	Nonesterified Fatty Acids (NEFA)IBA 07/2019 - 11/2003
2	AnticoagulantsIBA 01/2018 - 10/2016
2	Glycerol (Glycerine)FDA LinkGeneric 12/2016 - 09/2008
2	SolutionsIBA 01/2014 - 12/2008
2	Adiponectin ReceptorsIBA 06/2011 - 05/2010
2	CholesterolIBA 06/2011 - 05/2010
2	Biotin (Vitamin H)FDA Link 05/2008 - 02/2007
2	HomocysteineIBA 02/2008 - 12/2006
1	Leucine (L-Leucine)FDA Link 03/2024
1	CalciumIBA 01/2024
1	edoxabanIBA 12/2023
1	Atrial Natriuretic Factor (ANF)IBA 11/2023
1	Natriuretic PeptidesIBA 11/2023
1	Brain Natriuretic Peptide (Natrecor)FDA Link 11/2023
1	Rituximab (Mabthera)FDA Link 01/2023
1	Type A Botulinum Toxins (Botox)FDA Link 12/2022
1	incobotulinumtoxinA FDA Link 12/2022
1	AutoantibodiesIBA 01/2022
1	AntibodiesIBA 01/2022
1	SteroidsIBA 12/2021
1	Adenosine Triphosphate (ATP)IBA 10/2021

Therapy/Procedure

7	Therapeutics 11/2023 - 04/2003
4	Catheter Ablation 12/2023 - 01/2019
3	Parathyroidectomy 01/2023 - 01/2022
2	Kidney Transplantation 01/2024 - 10/2023
2	Cardiac Resynchronization Therapy 12/2021 - 11/2016
2	Defibrillators (Defibrillator) 12/2021 - 01/2021
2	Drug Therapy (Chemotherapy) 12/2021 - 11/2015
1	Nephrectomy 05/2024
1	Cryosurgery 12/2023
1	Thymectomy 01/2023
1	Osteotomy 09/2022
1	Transplantation 01/2022